2019, Cilt 17, Sayı 1, Sayfa(lar) 042-047 |
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Unnecessary Repeated Total PSA Tests; Evaluation with Minimum Retest Interval and Reference Change Value |
Nergiz Zorbozan1, İlker Akarken2 |
1Pamukkale Üniversitesi Tıp. Fakültesi, Tıbbi Biyokimya, Denizli, Türkiye 2Muğla Sıtkı Koçman Üniversitesi, Üroloji Anabilim Dalı, Muğla, Türkiye |
Keywords: Health Care Costs; cost Savings; prostate specific antigen; laboratory Markers |
Objective: The aim of study was to determine unnecessary repeated total prostate specific
antigen(tPSA) according to minimum retest interval and to evaluate the change between consecutive
measurement results with RCV.
Material and Methods: According to report of Association for Clinical Biochemistry and Laboratory
Medicine, when first result is raised, it is recommended to repeat tPSA once in 6 weeks to assess the
trend. tPSA test results which were requested between March 2015 and 2017 in our hospital were
evaluated retrospectively. If tPSA was>2.5 ng/mL and this test was repeated in less than 6 weeks, it was
determined as unnecessary repeated test. RCV was calculated.
Results: The number of tPSA was 1794 and number of consecutive tPSA requested was 427 (12.5%).
The first tPSA result was>2.5 ng/mL in 46.4% (198/427) of consecutive tPSA tests, 49% of these
tests(97/198) were unnecessary. RCV was calculated as 51.45%. In 82.5% (80/97) of unnecessary
repeated tPSA, the change between two results was smaller than RCV. Number of consecutive tests
which changed below RCV was significantly lower in appropriately requested tPSA tests than
unnecessary repeated tPSA (p=0,002).
Conclusion: Absence of significant difference between two consecutive results in unnecessary repeated
test according to RCV suggests the importance of test requesting according to guidelines. We believe
that our work will raise awareness about reducing unnecessary requests.
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