2015, Cilt 13, Sayı 1, Sayfa(lar) 029-034 |
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Beta Thalassemia Trait Accompanying Iron Deficiency Anemia |
Hülya Ünal, Ayşenur Atay, Erkan Söğüt, Leyla Demir, Saliha Aksun, Recep Sütçü |
İzmir Katip Çelebi Üniversitesi, Atatürk Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya Bölümü, İzmir, Türkiye |
Keywords: Thalassemia; iron deficiency anemia; ferritin |
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Objective: Anemia is a commonly encountered health problem. In this study, togetherness of beta
thalassemia trait with iron deficiency anemia was investigated using by some biochemical and
hematological cell count indices.
Material and Methods: The 128 specimens of whole blood samples (n = 895) that were sent to our
laboratory were selected as beta thalassemia carriers by hematological indices and HbA2 values. The hemoglobin chain analysis was performed by high performance liquid chromatography method.
Complete blood count, serum iron, total iron binding capacity, serum ferritin level, Mentzer Index and
transferrin saturation index were retrospectively evaluated.
Results: In all carriers included in the review, 63 % were females, 23 % were men and 14 % were
children under the age of 16. Although low ferritin levels were observed in only one carrier of each men
and children group, in female carriers this was found as 28 %. Mentzer Index was found higher than 13
in 20 % of female, 3 % of men and 6 % of children carriers. Transferrin saturation index was found
lower than 10 % in 14 % of female, 10 % of men and 11 % of children carriers groups.
Conclusion: Especially in female and child beta thalassemia carriers, it should be taken into account
the possible togetherness with the iron deficiency during the treatment period,. |
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