2020, Cilt 18, Sayı 2, Sayfa(lar) 107-113 |
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Retrospective Determination of Substance Use Distribution in Addicts Based on Laboratory Data |
Uğur Atik1, M. Burak Y. Çimen2 |
1Üsküdar Üniversitesi, Tıbbi Biyokimya Laboratuvarı, İstanbul, Türkiye 2Mersin Üniversitesi Tıp Fakültesi Tıbbi Biyokimya Anabilim Dalı, Mersin, Türkiye |
Keywords: Addictive Substances, Urine, LC/MS/MS, Alcohol, Cannabis, Cocaine, MDMA |
Objectives: There are not enough studies based on laboratory results regarding the prevalence of
Substance Use Disorders in our country, The purpose of this retrospective study is; to determine the
distribution of the substances used by dependent individuals with treatment desire according to age,
gender and laboratory data and to share the results of this wide sampling.
Methods: In 9402 urine samples between 2015-2020; analysis of alcohol, amphetamine, 3,4-
methylenedioxy-N-methylamfetamine, cannabis, cocaine and morphine were performed by ultraperformance
liquid chromotography coupled with tandem mass spectrometry (LC/ MS/ MS).
Results: Reportable levels of items were determined in 3792 samples of 2274 individuals. General
mean age was calculated as 31.14 ± 9.32. The addictive substance users were found mostly between
age 25-29 for men (23.8%) and 20-24 (20%) for women. It was determined that female between the
ages of 14-19 use more substances (14.8%) than male who are in the same age range (%5.14) (p
<0.001). The most used item ranking was; cannabis, alcohol, cocaine (40.2%, 24.1%, 19.6%) and
cannabis users were observed to increase each year. In samples with more than one substance; there
were 2 (21%) and 3-6 (5%) different substances. Those who used multiple substances also chose more
cannabis, alcohol and cocaine.
Conclusion: The results of this study showed differences between; Turkey and the European Union
drug reports and with some regional studies. There are some differences in the particularly the most
widely used material ranking but a similarity in the increasing of cannabis use. Some similarities were
found in the profile of substance users by age ranges and genders. Diagnosis, treatment and follow-up
will be made by the more widespread use of laboratory data from large epidemiological studies, Turkey
will help to achieve more concrete results in general.
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