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2015, Cilt 13, Sayı 1, Sayfa(lar) 029-034
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Beta Thalassemia Trait Accompanying Iron Deficiency Anemia
Hülya Ünal, Ayşenur Atay, Erkan Söğüt, Leyla Demir, Saliha Aksun, Recep Sütçü
İzmir Katip Çelebi Üniversitesi, Atatürk Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya Bölümü, İzmir, Türkiye
Keywords: Thalassemia; iron deficiency anemia; ferritin

Objective: Anemia is a commonly encountered health problem. In this study, togetherness of beta thalassemia trait with iron deficiency anemia was investigated using by some biochemical and hematological cell count indices.

Material and Methods: The 128 specimens of whole blood samples (n = 895) that were sent to our laboratory were selected as beta thalassemia carriers by hematological indices and HbA2 values. The hemoglobin chain analysis was performed by high performance liquid chromatography method. Complete blood count, serum iron, total iron binding capacity, serum ferritin level, Mentzer Index and transferrin saturation index were retrospectively evaluated.

Results: In all carriers included in the review, 63 % were females, 23 % were men and 14 % were children under the age of 16. Although low ferritin levels were observed in only one carrier of each men and children group, in female carriers this was found as 28 %. Mentzer Index was found higher than 13 in 20 % of female, 3 % of men and 6 % of children carriers. Transferrin saturation index was found lower than 10 % in 14 % of female, 10 % of men and 11 % of children carriers groups.

Conclusion: Especially in female and child beta thalassemia carriers, it should be taken into account the possible togetherness with the iron deficiency during the treatment period,.


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