The aim of the present study is to investigate the relation between new obesity indices waist
circumference/height (WtHR), visceral adiposity index (VAI) and body adiposity index (BAI) and
homeostasis model assessment of insülin resistance (HOMA-IR) index and pancreatic beta cell function
in healthy adult men.
Materials and Methods: Non-smoker and non-drinker 51 healthy adult men whose HOMA-IR index
were under the 2,5 included to this study. Fasting serum glucose, triglyceride, HDL, insulin and Cpeptide
levels were measured and body mass index (BMI), WtHR, BAI and VAI were calculated. Insulin
resistance was considered by HOMA-IR index; beta cell function and insulin secretion were considered
by serum C-peptide level. Pearson's correlation test was performed to correlation analysis.
Results: WtHR showed positive correlations with serum glucose, insülin and C-peptide levels (r values
were; 0,411; 0,341 and 0,451 respectively). In addition BMI showed positive correlations with serum
glucose, insülin and C-peptide levels too (r values were; 0,424; 0,396 and 0,473 respectively). VAI
showed positive correlations with serum glucose and C-peptide levels (r values were; 0,725 and 0,354
respectively). BAI was not correlated with any biochemical parameters excepted HOMA-IR index. There
were positive correlations between the HOMA-IR index and all of the obesity indices (r values were
0,434; 0,455; 0,526 and 0,572 respectively for BAI, VAI, WHtR and BMI).
Conclusion: WtHR and BMI showed the strongest relationships with beta cell activity and insülin
resistance. WHtR is the most reminder of BMI in this aspect. Although some metabolic parameters were
used in calculation of VAI, it showed similar results to other indices. Whereas BAI was related to insülin
resistance, it wasn't related to insülin secretion.