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2020, Cilt 18, Sayı 2, Sayfa(lar) 107-113
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Retrospective Determination of Substance Use Distribution in Addicts Based on Laboratory Data
Uğur Atik1, M. Burak Y. Çimen2
1Üsküdar Üniversitesi, Tıbbi Biyokimya Laboratuvarı, İstanbul, Türkiye
2Mersin Üniversitesi Tıp Fakültesi Tıbbi Biyokimya Anabilim Dalı, Mersin, Türkiye
Keywords: Addictive Substances, Urine, LC/MS/MS, Alcohol, Cannabis, Cocaine, MDMA

Objectives: There are not enough studies based on laboratory results regarding the prevalence of Substance Use Disorders in our country, The purpose of this retrospective study is; to determine the distribution of the substances used by dependent individuals with treatment desire according to age, gender and laboratory data and to share the results of this wide sampling.

Methods: In 9402 urine samples between 2015-2020; analysis of alcohol, amphetamine, 3,4- methylenedioxy-N-methylamfetamine, cannabis, cocaine and morphine were performed by ultraperformance liquid chromotography coupled with tandem mass spectrometry (LC/ MS/ MS).

Results: Reportable levels of items were determined in 3792 samples of 2274 individuals. General mean age was calculated as 31.14 ± 9.32. The addictive substance users were found mostly between age 25-29 for men (23.8%) and 20-24 (20%) for women. It was determined that female between the ages of 14-19 use more substances (14.8%) than male who are in the same age range (%5.14) (p <0.001). The most used item ranking was; cannabis, alcohol, cocaine (40.2%, 24.1%, 19.6%) and cannabis users were observed to increase each year. In samples with more than one substance; there were 2 (21%) and 3-6 (5%) different substances. Those who used multiple substances also chose more cannabis, alcohol and cocaine.

Conclusion: The results of this study showed differences between; Turkey and the European Union drug reports and with some regional studies. There are some differences in the particularly the most widely used material ranking but a similarity in the increasing of cannabis use. Some similarities were found in the profile of substance users by age ranges and genders. Diagnosis, treatment and follow-up will be made by the more widespread use of laboratory data from large epidemiological studies, Turkey will help to achieve more concrete results in general.


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