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2004, Cilt 2, Sayı 1, Sayfa(lar) 041-049
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Biochemical Mechanisms in Hyperhomocysteinemia
Ramazan Memişoğulları, Fatih Akçay
Atatürk Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı, Erzurum
Keywords: Homocysteine, lipid peroxidation, coagulation, endothelium, adenosine

Hyperhomocysteinemia is a recently recognized independent risk factor for cardiovascular diseases. Although the mechanism of vascular damage in hyperhomocysteinemia has not been completely understood, it may lead to this condition by increasing free radical production and lipid peroxidation, disturbing endothelial functions, thrombocyte functions, or coagulation system, and also causing a decrease in adenosine production.

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