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2016, Cilt 14, Sayı 2, Sayfa(lar) 144-156
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Monitoring Anti-platelet Therapy with Platelet Function Testing
Burcu Barutçuoğlu
Ege Üniversitesi Tıp Fakültesi, Klinik Biyokimya Bilim Dalı, İzmir
Keywords: Thrombocytes; platelet function tests; antiplatelet drugs

It is known that anti-platelet drugs reduce the vascular pathologies in patients with cardiovascular disease. Despite using these drugs there are still a number of patients suffering from vascular events. Even though monitoring antiplatelet drug therapy with platelet function tests is contentious, they are widely in use. The wide variety of available platelet function tests using different methodologies, the apparent lack of standardization, and emerging evidence on the clinical value of platelet function testing are resulting in a considerable uncertainty in the clinical practice, Nevertheless, platelet function testing has clinical benefits for the patients and also helps in identifying the right drug at the right dose for the right patient. In this review article, platelet activation, formation of thrombosis, up-to-date platelet function tests and drug resistance in patients receiving anti-platelet drugs will be discussed.

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