2015, Cilt 13, Sayı 1, Sayfa(lar) 015-020 |
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Levels of Ferritin, Vitamin B12 and Folic Acid in Patients with Vitiligo in Usak Region |
Arzu Akağaç Etem1, Ebru Önalan Etem2, Sembol Türkmen Yıldırmak3, Mehmet Kırtay4 |
1Uşak Devlet Hastanesi, Tıbbi Biyokimya, Uşak, Türkiye 2Fırat Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji, Elazığ, Türkiye 3Okmeydanı Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya, İstanbul, Türkiye 4Erciyes üniversitesi, Mühendislik Fakültesi, Bilgisayar Mühendisliği, Kayseri, Türkiye |
Keywords: Vitiligo; ferritin; vitamin B12; folic Acid |
Objective: Vitiligo is an acquired depigmentation disorder occur with destruction of melanocytes, a
common skin disease. We aimed to investigate ferritin, vitamin B12 and folic acid levels in patients with
vitiligo in Usak region.
Material and Methods: A hundred and two cases with vitiligo (60 female and 42 male) and a hundred
and two control subjects (60 female and 42 male) were enrolled in this study. Ferritin, vitamin B12 and
folic levels were measured by Advia Centaur XP (Siemens, USA). The collected data were analyzed by
SPSS version11.5.
Results: Comparing the patients and control subjects, the mean values of ferritin were found a
statistically significant difference between groups (p = 0.664). The mean values of vitamin B12 and folic
acid have detected statistically significant difference between groups (p = 0.041 and p = 0.025,
respectively).
Conclusion: Vitamin B12 and folic acid may play a role in the pathogenesis of vitiligo disease. We
recommend that vitamin B12 and folic acid deficiency in patients with vitiligo were evaluated in the
outpatient clinical examination and laboratory tests are done periodically in follow-up.
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