Ana Sayfa | Amaç ve Kapsam | Dergi Hakkında | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2015, Cilt 13, Sayı 1, Sayfa(lar) 015-020
[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Levels of Ferritin, Vitamin B12 and Folic Acid in Patients with Vitiligo in Usak Region
Arzu Akağaç Etem1, Ebru Önalan Etem2, Sembol Türkmen Yıldırmak3, Mehmet Kırtay4
1Uşak Devlet Hastanesi, Tıbbi Biyokimya, Uşak, Türkiye
2Fırat Üniversitesi, Tıp Fakültesi, Tıbbi Biyoloji, Elazığ, Türkiye
3Okmeydanı Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya, İstanbul, Türkiye
4Erciyes üniversitesi, Mühendislik Fakültesi, Bilgisayar Mühendisliği, Kayseri, Türkiye
Keywords: Vitiligo; ferritin; vitamin B12; folic Acid

Objective: Vitiligo is an acquired depigmentation disorder occur with destruction of melanocytes, a common skin disease. We aimed to investigate ferritin, vitamin B12 and folic acid levels in patients with vitiligo in Usak region.

Material and Methods: A hundred and two cases with vitiligo (60 female and 42 male) and a hundred and two control subjects (60 female and 42 male) were enrolled in this study. Ferritin, vitamin B12 and folic levels were measured by Advia Centaur XP (Siemens, USA). The collected data were analyzed by SPSS version11.5.

Results: Comparing the patients and control subjects, the mean values of ferritin were found a statistically significant difference between groups (p = 0.664). The mean values of vitamin B12 and folic acid have detected statistically significant difference between groups (p = 0.041 and p = 0.025, respectively).

Conclusion: Vitamin B12 and folic acid may play a role in the pathogenesis of vitiligo disease. We recommend that vitamin B12 and folic acid deficiency in patients with vitiligo were evaluated in the outpatient clinical examination and laboratory tests are done periodically in follow-up.


[ Türkçe Özet ] [ PDF ] [ Benzer Makaleler ]
Ana Sayfa | Amaç ve Kapsam | Dergi Hakkında | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim