Ana Sayfa | Amaç ve Kapsam | Dergi Hakkında | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | İletişim  
2013, Cilt 11, Sayı 3, Sayfa(lar) 093-097
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Inflammation Biomarkers in Patients with Acute Myocardial Infarction
Ayfer Aydoğdu Çolak1, Tuba Hancı2, Neşe Doğan1, Şergır Matlaş3, İsmail Karademirci1, Füsun Üstüner1
1Tepecik Eğitim ve Araştırma Hastanesi, Klinik Biyokimya Bölümü, İzmir
2Dışkapı Eğitim ve Araştırma Hastanesi, Klinik Biyokimya Bölümü, Ankara
3Tepecik Eğitim ve Araştırma Hastanesi, Dahiliye Bölümü, İzmir
Keywords: Myocardial Infarction; procalcitonin; C-Reactive Protein

Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases. In this study we aimed to evaluate the prognostic significance of alterations in C-reactive protein (CRP) and procalcitonin levels, in male patients with acute myocardial infarction (AMI).

Materials and Methods: 34 male patients admitted to emergency department for angina pectoris and diagnosed with AMI were included in the study. Patients with obesity smoking and chronic diseases were excluded. Cardiac tests were performed immediately at admission. hsCRP and procalcitonin concentrations of AMI patients were measured at the time of admission and at 48 hours after the admission with chemiluminescence immunassay.

Results: HsCRP concentrations of 34 male patients aged 58.6±11.3 (mean±SD) were 4.1±3.8 and 43.5±34.5 mg/dl respectively at admission and 48th hour, procalcitonin concentrations were 0.29±1.4 ve 0.93±3.2 ng/mL respectively at admission and 48 hours after admission. 0 and 48th hour concentrations of both hsCRP and procalcitonin were significantly different (p<0.05).

Conclusion: A significant increase was detected in 48th hour hsCRP and procalcitonin levels compared with baseline values. HsCRP and procalcitonin can be valuable follow up parameters during hospital stay in AMI patients.


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