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2008, Cilt 6, Sayı 3, Sayfa(lar) 095-098
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Evaluation of Accuracy of Immuno-Turbidimetric D-Dimer Method
Güler Buğdaycı, Erdinç Serin, Fatih Özcan
Abant Üzzet Baysal Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Gölköy, Bolu
Keywords: Fibrin Fragment D, plasma, laboratory techniques and procedures, emergency service, hospital

Objective: The objective of this study was to evaluate of accuracy of the immuno-turbidimetric method.

Material and Methods: Patients (n=160) were tested with the D-Dimer assay with a STalia ® D-DI (D-dimer) (Diagnostica Stago, Asnieres, France). D-dimer plasma concentration were measured with the STalia ® D-Di and our reference method was the ELISA technique (Asserachrom®, Diagnostica Stago, Asnieres, France). The Stalia® D-Di is a semi-automated system for the quantification of D-dimer using an immunoturbidimetrik method incorporating a suspension of latex micropartiles coated with two different monoclonal antibodies specifically targeted against human D-dimer fragmants.

Results: The correlation between the results of STalia D-Di and Asserachrom D-Di evaluation of accuracy was acceptable (y=0.913x+ 0.077, r=0.970, Sy/x= 0.24).

Conclusion: STalia D-Di was analytically found to be a proper method to evaluate D-Di.


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