2017, Cilt 15, Sayı 3, Sayfa(lar) 114-118 |
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Appropriateness of Thyroid Function Test Requesting to the Foreseen Algorithm in Giresun Province Center |
Y Sembol Yıldırmak1, Murat Usta1, Ömer Emecen2, Oğuz Dikbaş3 |
1Giresun Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Giresun, Türkiye 2SB Giresun Kamu Hastaneler Birliği, Giresun Üniversitesi Prof Dr A.İlhan Özdemir Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya, Giresun, Türkiye 3Giresun Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Giresun, Türkiye |
Keywords: Algorithm; free thyroxine; free triiodothyronine; thyroid stimulating hormone |
Objective: It is reported that the first tests to evaluate thyroid functions in the guidelines of American
Thyroid Association (ATA), American Association of Clinic Endocrinologs (AACE) and Turkey
Endocrinology and Metabolism Association are thyroid stimulated hormone (TSH) and free T4 (fT4). In
this study, it was aimed to investigate the appropriateness of thyroid function test requests to the
clinically foreseen algorithm in Giresun Province Center.
Materials and Methods: TSH, fT3 and fT4 test results, which were worked and reported between
01.01.2016 and 31.12.2016 in the Ministry of Health Prof.Dr.A.İlhan Özdemir State Hospital Medical
Biochemistry Laboratory, were obtained from the Laboratory Information System records. Thyroid
function tests were evaluated in 4 groups (Only TSH; TSH + fT4; TSH + fT3; TSH + fT3 + fT4). The
results of each group were divided into three subgroups: hypothyroidism, normothyroidism and
hyperthyroidism according to the reported TSH reference range (0.27-4.2 mIU / L).
Results: Thyroid function test panel requests (n = 65,533), TSH + fT4 is the cause of 47.8%, TSH is the
only cause of 34.3%, TSH + fT3 + fT4 is the 17.8% whereas TSH + fT3 was the cause. The percentage
of additional fT3 and fT4 test numbers (n = 44,025) was calculated as 36.6% within the total number of
tests (n = 120,308) required in the normothyroidic groups determined according to the TSH reference
range (0.27-4.2 mIU / L).
Conclusion: According to the clinically foreseen algorithm for thyroid function tests, it was determined
that fT3 and fT4 test requests together with TSH were used together with not being widespread when
only TSH should be done. In addition, compared to the results obtained in different centers, it has been
observed that the demand for thyroid function test in Giresun province center is more acceptable than
that of the clinically prescribed algorithm.
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