2012, Cilt 10, Sayı 3, Sayfa(lar) 085-089 |
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Insulin Resistance and Serum IL-8 Levels of Obese Individuals with Normal Glucose Tolerance |
Ayfer Aydoğdu Çolak1, Hakan Türkön2, Hülya Yalçın1, Işıl Çoker1 |
1S.B. Tepecik Eğitim ve Araştırma Hastanesi, Tıbbi Biyokimya Anabilim Dalı, İzmir 2Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Çanakkale |
Keywords: Obesity; Insulin Resistance; IL-8 |
Objective: The aim of this study is to determine the correlation between insulin resistance and serum IL-8 levels of obese individuals with normal glucose tolerance.
Materials and Methods: 72 obese individuals with the ages ranging from 20 to 59 and with BMI(body mass index) higher than 30 were included in the study.34 individuals with non insulin resistance were considered as control group and 38 individuals with insulin resistance were considered as patient group.Anthropometric and biochemical characteristics of the individuals were researched. Serum IL-8 and insulin levels were measured by chemiluminescence immunoassay method.
Results: Serum IL-8 levels of patient group were significantly higher than control group (p<0,05).
Conclusion: We consider that determining serum IL-8 levels of obese individuals developing insulin resistance can be useful to prevent from the possible risks.
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